VIDA - Air Trapping

Air trapping (aka "gas trapping"), the retention of excess gas in all or part of the lung, can arise from several causes including complete or partial airway obstruction such as COPD, Asthma and Bronchiolitis Obliterans Syndrome (BOS).

On a chest CT image, air trapping is seen as a decreased attenuation of pulmonary parenchyma, especially manifested as a less than normal increase in attenuation during expiratory acquisition.

Air trapping can be seen in approximately 50% of CT thorax examinations¹, though mild air trapping (<25%) may be deemed clinically insignificant.⁶
COPD is significantly under-diagnosed--as much as 70% of the true COPD population is not yet diagnosed.⁵ Today's conventional diagnostic methods miss 21.4% of COPD patients, often including PRISm patients.²
Because Asthma and COPD have a number of similarities, it can be challenging to distinguish using today's conventional tests.³
Up to half of lung transplant recipients develop BOS within five years of transplant. One of the earliest signs of BOS is air trapping.⁴

[1] Tanaka N, Matsumoto T, Miura G, et al. Air trapping at CT: high prevalence in asymptomatic subjects with normal pulmonary function. Radiology. 2003;227(3):776-785.
[2] Lowe KE, Regan EA, Anzueto A, et al. COPDGene 2019: redefining the diagnosis of chronic obstructive pulmonary disease. Chronic Obstr Pulm Dis. 2019; 6(5): 384-399.
[3] Athanazio R. Airway disease: similarities and differences between asthma, COPD and bronchiectasis. Clinics (Sao Paulo). 2012;67(11):1335-1343.
[4] Am J Respir Crit Care Med Vol. 193, P19-P20, 2016 ATS Patient Education Series © 2016 American Thoracic Society
[5] Diab, Underdiagnosis and Overdiagnosis of Chronic Obstructive Pulmonary Disease, ATS, (Link)
[6] Miller WT, Chatzkel J, Hewitt MG. Expiratory air trapping on thoracic computed tomography. A diagnostic subclassification. Ann Am Thorac Soc. 2014;11 (6): 874-81

vDPM, AirTrapping Enhanced

VIDA’s Air Trapping ventilation-defect probability map (vDPM) supports earlier identification and tracking of obstructive small airway defects, which may help in disease diagnosis for COPD, Asthma, and bronchiolitis obliterans (BOS).

This analysis is produced from VIDA’s vDPM patented technique using image registration of an inspiratory (TLC) and expiratory (RV) CT scan pair to delineate ventilation abnormalities for small airway defects (fSAD) and tissue loss (emphysema).

Inspiratory/Expiratory registration for structure loss vs air trapping

Sophisticated methodology transcends other air trapping techniques with both absolute density & change in density

Validated & 510k cleared with 5,000+ air trapping scans analyzed

VIDA AirTrapping (vDPM)

VIDA's Air Trapping empowers clinicians with Lung Intelligence

Additional Resources